Laboratory of System Medicine for Healthy Aging

• We have proposed and have been developing an integrative approach to solving this problem that accounts all the listed factors. The conclusion concerning the decisive role of the interaction between the three main types of genome present in the human organism – nuclear, mitochondrial, and microbiotic - is especially.
• The Laboratory has been developing a concept of aging as an inflammatory process related to increase of the number of old cells in tissues and propagation of weak inflammatory reaction. This universal process spans like an axis through the whole organism from the intestines to the brain and it is «carried» by active molecules of the so-called «aging phenotype» that cause immune response and provoke aging of cells.

Education and career development: We have organized internships at the University of Bologna (Italy) for 2 students, 2 postgraduates, and 3 young scientists.

Organizational and structural changes:

On the grounds of the Laboratory an interdisciplinary scientific and practical center of healthy aging and active longevity has been created. It incorporates departments of bioinformatics, aging biology and sociology.

Collaborations:

University of Bologna (Italy), University College London (United Kingdom), Rey Juan Carlos University Madrid (Spain): joint research