In recent years, the scientific research in the field of MRI (magnetic resonance imaging, one of the most important non-invasive medical imaging methods) has been focused on the development of quantitative methods aimed the search for biomarkers for the early diagnostics and the assessment of the activity of diseases as well as of the efficiency of therapeutic strategies. In spite of the interest and promising prospects, these quantitative methods are not widely implemented in daily clinical practice, perhaps, due to the limitations of the internation between physicists and medical professionals who work on problems of magnetic resonance.
Name of the project: Advanced quantitative technologies in magnetic resonance imaging for the detection of the stages of inflammation and fibrosis as markers of diseases.
To achieve the goals of the project, the following tasks have been set for the team:
- To develop new radio-frequency coils (RF coils) and substrates based on materials with high dielectric permeability and «artificial» materials with special electromagnetic properties for the improvement of the signal-to-noise ratio, the resolution of images, the homogeneity of the magnetic field in the area of interest, as well as the RF safety;
- To develop special quantitative MRI methods and protocols for the early detection and control of inflammation and fibrosis in specific organs;
- To develop post-processing methods on the basis of deep learning for the collection of quantitative metrics magnetic resonance images;
- To research specific biomarkers for the assessment of the activity of diseases and the determination of the efficiency of therapeutic strategies.
Hosting organization
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Field of studies
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City
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Invited researcher
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Time span of the project
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«Smart Sleep» Laboratory
Saratov State University |
Health studies |
Saratov |
Thomas Penzel |
2019-2021 |
Laboratory of Experimental Oncology
N. I. Pirogov Russian National Research Medical University of the Ministry of Health of the Russian Federation |
Health studies |
Moscow |
Marcus Conrad |
2019-2021 |
Laboratory of the Oncology Research Center of the School of Chemical and Biomedical Technologies
Tomsk Polytechnic University |
Health studies |
Tomsk |
Tolmachev Vladimir Maximilianovich
Sweden, Russia |
2019-2021 |