International Associated Laboratory «Developmental Neurobiology»

• We have found special forms of activity in sensory cerebral cortex of newborns and explored mechanisms of their generation. These observations have been compared to development of brains of human newborns.
• Our researchers have found important features of development of inhibition in the nervous system in normal conditions and in the presence of pathological states, in particular «switching» of the GABA neuromediator from inhibition to excitation as a result of brain injury. We also found that even in doses that do not cause pathologies in adult brain alcohol has neurotoxic impact on some immature neurons by blocking early forms of brain activity.

Implemented results of research: Developed methods of research of cerebral cortices of prematurely born babies are used in perinatal centers all around the world.

Education and career development:

• A masters program in neurobiology has been introduced at the Kazan Federal University, a course in physiology of the nervous system in ontogenesis has been created.
• We have developed methodological textbooks: «Physiology of the nervous system», «Physiology of excitable systems», «Early gamma-oscillations», «Neonatal cortical rhythms», «Spontaneous activity in developing neural networks».
• 17 young researchers, postgraduates and students have completed internships.
• We have conducted scientific schools: «Mechanisms of adaptation of growing organisms to physical and cognitive load» (2012), «From neuron to brain» (2013, in English), «Technological trends in neurobiology» (2013,  in English), «From neuron to brain: extended neurobiology course» (2015, 2016).
• 5 candidate dissertations and 1 doctoral dissertation have been defended

Organizational and structural changes:

The Open Laboratory of Neurobiology has been created where research groups have been formed to study pathophysiology of pain and migraine, synaptic plasticity, gaseous mediatoin the nervous system.

Collaborations:

• National Institute of Health and Medical Research – INSERM (France): creation of a Russian-French laboratory «Development neurobiology», conducting international conferences «From neuron to brain» (2013, 2014, 2015), «Translational medicine» (2016) and the «From neuron to brain: extended course in neurophysiology» science and practice school (2015, 2016), joint research and internships of employees 
• University of Eastern Finland (Finland): double postgraduate degree programs, conducting the «Modern technologies in neurobiology» conference (2013) and the «Advanced methods in neurophysiology» scientific school (September 2018)
• Heidelberg University (Germany): joint research, internships of employees