Molecular Neural Degeneration Laboratory (MNDL)
This laboratory was established as part of a scientific research project supported with a monetary grant awarded by the Government of the Russian Federation under a grant competition designed to provide governmental support to scientific research projects implemented under the supervision of the world's leading scientists at Russian institutions of higher learning (Resolution of the RF Government No.220 of April 9, 2010).
Grant Agreement No.: 11.G34.31.0056
Name of the institution of higher learning:
Federal state budget educational institution of higher professional learning "St. Petersburg State Polytechnic University"
Fields of scientific research:
Medical sciences and technologies
To establish a Molecular Neural Degeneration Laboratory at the Department of medical physics and bioengineering of the St. Petersburg State Polytechnic University.
Key project objectives:
To research molecular mechanisms responsible for neurodegenerative conditions, such as Alzheimer's disease (AD) and Huntington's disease (HD), as well as spinal-cerebellar ataxias (SCA). Research activities will be performed using laboratory mice affected by AD, HD, and SCA, as well as modern molecular, structural, and electrophysiological methods.
Anticipated scientific outcomes:
The project will help understand the molecular causes of these conditions and identify potential objects for the development of pharmaceuticals and therapy methods. The creation of this laboratory is precipitated by the need to develop such pharmaceuticals, as well as to train undergraduate and graduate students at the St. Petersburg State Polytechnic University.
Leading scientist's full name: Ilya Borisovich Bezprozvanny
Academic degrees and titles:
1992 – candidate of biological sciences, specialty: cellular biology, Institute of Cytology of the Russian Academy of Sciences, St. Petersburg, Russia.
2010 – doctor of biological sciences, specialty: cellular biology, Institute of Cytology of the Russian Academy of Sciences, St. Petersburg, Russia.
Deputy Director of the molecular neural degeneration laboratory at the Department of medical physics and bioengineering of the Institute of Physics, Nanotechnologies, and Telecommunications of the St. Petersburg State Polytechnic University; professor in Alzheimer's Research at the Department of Physiology of the Southwestern Medical Center of the University of Texas, Dallas, Texas, USA.
Areas of scientific interest:
Molecular and cellular medicine; investigation of the mechanisms responsible for neural degenerative conditions and development of new approaches to their treatment.